Combat Tweaks [The creator of this mod tries not to stray too much from vanilla gameplay, but they've adjusted quite a few things to make combat more enjoyable while still maintaining a good overall balance.It's really useful if you're playing on a harder difficulty and need to strategize. Advanced Tactics [This one really expands the tactics system and follower/AI behavior.This replaces all of the low-res textures with high-res versions and is probably the most popular texture mod out there. Origins is an amazing game, but the vanilla textures are horribly outdated.
JB3 Textures [This is a must-have if you have no other texture mods.As far as graphics and gameplay go, here are some that haven't been listed yet: I'd recommend not going crazy with mods if it's your first playthrough, but there are several that can definitely be considered essential depending on what you're looking for.